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Swamy KB, 2010
University Darul Iman Malaysia
International Anatomical Sciences and Cell Biology Conference 2010
http://www.med.nus.edu.sg/ant/iascbc2010/attachments/abstracts/Abstracts_Poster_Presentations_1.pdf
MATERIALS & METHODS: For the present study 1010 infants/ fetuses from King George Hospital and Victoria Government hospitals Visakhapatnam, India, during the period 2004 and 2006 were taken and studied that 17 subjects were found with congenital anomalies. Personal and maternal details of pregnant women i.e. age, consanguinity and maternal details like gravida, parity, history of any affected siblings in the family were recorded. Photographs and X-ray photographs of infants/fetuses were taken. The dead fetuses were embalmed with 10% formalin and preserved for further investigations.
SUMMARY AND RESULTS: From the above study of 17 congenital anomalous babies, 11 (64.70%) had consanguineous parents. 15 out of 17 (88.23 %) abnormal babies were born to young mothers, whereas out of 76 elderly (above 35 years of age) mothers, only 2 mothers (2.63% ) delivered anomalous babies and out of 934 young mothers only 15 (1.60 %) gave birth to abnormal babies. Comparative study showed that 9 (1.11%) out of 808 primi gravidas, 7 (3.68 %) out of multigravidae, and 1(8.33 %) out of total grand multigravidae, gave birth to abnormal babies. It shows that there is significant increase in incidence of abnormal babies to beget to elderly women. There are 13 types of anomalies recognised such as–anencephaly-5, Hydrocephaly-1, Cleft lip and palate-1,Talipus equinovarus-1, Congenital hydrocoele-1, Turner’s syndrome-1, Spinabifida with meningocoele-1, Exompholus-1, Bifid scrotum-1, Recto-urethral fistula-1, Sacrococcygeal tertoma-1, Ectopiavesicae-1 and Meningocoele-1.
CONCLUSIONS: The total number of infants/fetuses born are 1010 of which 563 were male, 447 are female. Among the 1010 new born 17(1.68%) were having congenital abnormaliti es. Out of 17 anomalous babies 14 are male and 3 are female. Consanguinity, maternal age, parity etc. influence the incidence of congenital anomalies.
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